Details for gene set INOH_NEGATIVE REGULATION OF (G ALPHA GDP-GTP EXCHANGE SIGNALING)[GSEA]

Table: GSEA Results Summary

Dataset	Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos
Phenotype	phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos
Upregulated in class	normalThy
GeneSet	INOH_NEGATIVE REGULATION OF (G ALPHA GDP-GTP EXCHANGE SIGNALING)
Enrichment Score (ES)	-0.82284737
Normalized Enrichment Score (NES)	-1.5659146
Nominal p-value	0.0037950664
FDR q-value	0.123395145
FWER p-Value	0.934

Fig 1: Enrichment plot: INOH_NEGATIVE REGULATION OF (G ALPHA GDP-GTP EXCHANGE SIGNALING)
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	RGS6	6040601	5364	0.109	-0.2807	No
2	RGS17	1400603	6491	0.061	-0.3369	No
3	RGS20	4540541 4730086	8495	0.019	-0.4433	No
4	RGS2	1090736	10477	-0.011	-0.5490	No
5	RGS13	3780722	10762	-0.016	-0.5632	No
6	RGS18	1780019	11006	-0.020	-0.5748	No
7	RGS7	3390044	11209	-0.023	-0.5841	No
8	RGS11	2360041	11734	-0.033	-0.6099	No
9	RGS4	2970711	13010	-0.067	-0.6738	No
10	RGS9	1050273	13796	-0.106	-0.7086	No
11	RGS3	60670 540736 1340180 1500369 3390735 4010131 4610402 6380114	14553	-0.173	-0.7370	No
12	RGS1	4060347 4540181	14916	-0.238	-0.7398	No
13	RGS19	7050427	15475	-0.398	-0.7418	Yes
14	RGS16	780091	16984	-1.327	-0.7296	Yes
15	RGS14	380086	18446	-5.536	-0.4190	Yes
16	RGS10	2340292	18498	-6.090	0.0063	Yes

Fig 3: INOH_NEGATIVE REGULATION OF (G ALPHA GDP-GTP EXCHANGE SIGNALING): Random ES distribution
Gene set null distribution of ES for INOH_NEGATIVE REGULATION OF (G ALPHA GDP-GTP EXCHANGE SIGNALING)